September 2024 - December 2024
Aging Institute
Guillermier C, Kumar NV, Bracken RC, Alvarez D, O’Keefe J, Gurkar A, Brown JD, Steinhauser ML. Nanoscale imaging of DNA-RNA identifies transcriptional plasticity at heterochromatin. Life Sci Alliance. 2024 Sep 17;7(12):e202402849. PMID: 39288993
Lv B, Dion WA, Yang H, Xun J, Kim DH, Zhu B, Tan JX. A TBK1-independent primordial function of STING in lysosomal biogenesis. Mol Cell. 2024 Oct 17;84(20):3979-3996.e9. PMID: 39423796.
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Liu J, Zuo Z, Fattah R, Finkel T, Leppla SH, Liu S. Anthrax lethal toxin exerts potent metabolic inhibition of the cardiovascular system. mBio. 2024 Nov 7:e0216024. PMID: 39508614
Cardiology
Koczo A, Acharya D, Ozbay B, Alharethi R, Givertz MM, Elkayam U, Schelbert EB, McNamara DM, Wong TC. CMR and adverse clinical outcomes in peripartum cardiomyopathy. Am Heart J Plus. 2024 Nov 9;48:100484. PMID: 39610381.
Chen C, Li S, Matsunaga TO, Pacella JJ, Everbach EC, Xie F, Porter TR, Villanueva FS, Chen X. Ischemia/Reperfusion Injury Enhances Accumulation of Perfluoropropane Droplets. Ultrasound Med Biol. 2024 Nov 10:S0301-5629(24)00408-3. PMID: 39523168.
Kundrick J, Saba KI, Naniwadekar A, Singla V, Mulukutla S, Thoma F, Bhonsale A, Kancharla K, Voigt A, Shalaby AA, Estes Iii NAM, Jain S, Saba S. Diastolic Dysfunction and the Risk of Stroke and Major Bleeding. Stroke. 2024 Dec;55(12):2856-2862. PMID: 39523999.
Classical Hematology
Yien YY. What does the FOX(O) say? High iron: hepcidin! Blood. 2024 Sep 19;144(12):1243-1245. PMID: 39298162.
Johnson AR, Rao K, Zhang BB, Mullet S, Goetzman E, Gelhaus S, Tejero J, Shiva S. Myoglobin inhibits breast cancer cell fatty acid oxidation and migration via heme-dependent oxidant production and not fatty acid binding. Free Radic Biol Med. 2024 Nov 20;225:208-220. PMID: 39368517.
Jones JM, Kaplan A, Chibisov I, Then J, Novelli EM, Kiss JE. Initial US tertiary health care system experience using caplacizumab in patients with immune thrombotic thrombocytopenic purpura. Ann Hematol. 2024 Nov;103(11):4449-4457. PMID: 39259327.
Endocrinology and Metabolism
Kubra S, Sun M, Dion W, Catak A, Luong H, Wang H, Pan Y, Liu JJ, Ponna A, Sipula I, Jurczak MJ, Liu S, Zhu B. Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health. bioRxiv [Preprint]. 2024 Sep 13:2024.09.13.612812. PMID: 39314427
Doerfler WR, Nikitski AV, Keating S, Spagnolo D, Kaya C, Morariu EM, Karslioglu French E, Yip L, Nikiforova MN, Wald AI, Nikiforov YE. Reappraisal of BRAFK601E-positive thyroid tumors in the NIFTP era. Endocr Relat Cancer. 2024 Nov 22;31(12):e240207. PMID: 39404355.
Quaytman JA, David NL, Venugopal S, Amorim T, Beatrice B, Toledo FGS, Miller RG, Steinhauser ML, Fazeli PK. Intermittent fasting for systemic triglyceride metabolic reprogramming (IFAST): Design and methods of a prospective, randomized, controlled trial. Contemp Clin Trials. 2024 Nov;146:107698. PMID: 39299543.
Gastroenterology, Hepatology and Nutrition
Karloski E, Dudley B, Diergaarde B, Blanco A, Everett JN, Levinson E, Rangarajan T, Stanich PP, Childers K, Brown S, Drogan C, Cavestro GM, Gordon K, Singh A, Simeone DM, Reich H, Kastrinos F, Zakalik D, Hampel H, Pearlman R, Gordon OK, Kupfer SS, Puzzono M, Zuppardo RA, Brand RE. The role of family history in predicting germline pathogenic variant carriers who develop pancreatic cancer: Results of a multicenter collaboration. Cancer. 2024 Oct 1;130(19):3297-3304. PMID: 38809542.
Celaj S, Estevez J, Novelli P, Orons P, Al-Khafaji A, Jonassaint NL, Cruz RJ, Malik SM. Challenges and Opportunities in the Adoption of p-TIPS for Acute Variceal Bleeding: Insights from a US Tertiary Center. Dig Dis Sci. 2024 Nov 25. PMID: 39586926.
Saloman JL, Jennings K, Stello K, Li S, Evans Phillips A, Hall K, Fogel EL, Vege SS, Andersen DK, Fisher WE, Forsmark CE, Hart PA, Pandol SJ, Park WG, Topazian MD, Van Den Eeden SK, Serrano J, Conwell DL, Li L, Yadav D; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Pancreatitis pain quality changes at year 1 follow-up, but GP130 remains a biomarker for pain. Pancreatology. 2024 Nov;24(7):993-1002. PMID: 39322454.
General Internal Medicine
Ruiter-Lopez L, Donohue JK, Vempalli H, Thurston RC, Levine MD, Snedaker K, Donnelly KZ, Okonkwo DO, Anto-Ocrah M. Resilience and Concussion Recovery in Minority Women: Promoting Health Equity. Neurotrauma Rep. 2024 Oct 9;5(1):989-997. PMID: 39440153.
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Jonassaint CR, Lalama CM, Carroll CP, Badawy SM, Hamm ME, Stinson J, Lalloo C, Saraf SL, Gordeuk VR, Cronin RM, Shah N, Lanzkron S, Liles DK, O’Brien JA, Trimnell C, Bailey L, Lawrence RH, Saint-Jean L, DeBaun MR, De Castro LM, Palermo T, Abebe KZ. Digital Cognitive Behavioral Therapy vs Education for Pain in Adults with Sickle Cell Disease. Blood Adv. 2024 Oct 7:bloodadvances.2024013861. PMID: 39374587.
Tadrous M, Callaway Kim K, Hernandez I, Rothenberger SD, Devine JW, Hershey TB, Maillart LM, Gellad WF, Suda KJ. Differences in Drug Shortages in the US and Canada. JAMA. 2024 Dec 10;332(22):1912-1922. 17688. PMID: 39480469.
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Geriatric Medicine
Greenspan SL, Perera S, Haeri NS, Nace DA, Resnick NM. Denosumab for osteoporosis in older adults in long-term care: A randomized trial. J Am Geriatr Soc. 2024 Nov 10. PMID: 39523676.
Murillo T, Mangal K, Barmada G, Morris T, Waggle KD, Griffith M, Pless LL, Harrison LH, Glista R, Wilson B, Snyder G, Nace DA. Transmission of Group A Streptococcus in Long-Term Care: An Outbreak Investigation. Am J Infect Control. 2024 Nov 20:S0196-6553(24)00849-6. PMID: 39577569.
Forman DE, Pignolo RJ. A Pragmatic Approach to Introducing Translational Geroscience Into the Clinic: A Paradigm Based on the Incremental Progression of Aging-Related Clinical Research. J Gerontol A Biol Sci Med Sci. 2024 Sep 1;79(9):glae062. PMID: 39126296.
Infectious Diseases
Shields RK, Dorazio AJ, Tiseo G, Squires KM, Leonildi A, Giordano C, Kline EG, Barnini S, Iovleva A, Griffith MP, Van Tyne D, Doi Y, Falcone M. Frequency of cefiderocol heteroresistance among patients treated with cefiderocol for carbapenem-resistant Acinetobacter baumannii infections. JAC Antimicrob Resist. 2024 Sep 9;6(5):dlae146. PMID: 39253335.
Heil EL, McCreary EK. REVISITing treatment of metallo-β-lactamases. Lancet Infect Dis. 2024 Oct 7:S1473-3099(24)00561-9. PMID: 39389074.
Durand CM, Massie A, Florman S, Liang T, Rana MM, Friedman-Moraco R, Gilbert A, Stock P, Mehta SA, Mehta S, Stosor V, Pereira MR, Morris MI, Hand J, Aslam S, Malinis M, Haidar G, Small CB, Santos CAQ, Schaenman J, Baddley J, Wojciechowski D, Blumberg EA, Ranganna K, Adebiyi O, Elias N, Castillo-Lugo JA, Giorgakis E, Apewokin S, Brown D, Ostrander D, Eby Y, Desai N, Naqvi F, Bagnasco S, Watson N, Brittain E, Odim J, Redd AD, Tobian AAR, Segev DL; HOPE in Action Investigators. Safety of Kidney Transplantation from Donors with HIV. N Engl J Med. 2024 Oct 17;391(15):1390-1401. PMID: 39413376.
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Malignant Hematology and Medical Oncology
Bao R, Hutson A, Madabhushi A, Jonsson VD, Rosario SR, Barnholtz-Sloan JS, Fertig EJ, Marathe H, Harris L, Altreuter J, Chen Q, Dignam J, Gentles AJ, Gonzalez-Kozlova E, Gnjatic S, Kim E, Long M, Morgan M, Ruppin E, Valen DV, Zhang H, Vokes N, Meerzaman D, Liu S, Van Allen EM, Xing Y. Ten challenges and opportunities in computational immuno-oncology. J Immunother Cancer. 2024 Oct 26;12(10):e009721. PMID: 39461879.
Davar D, Morrison RM, Dzutsev AK, Karunamurthy A, Chauvin JM, Amatore F, Deutsch JS, Das Neves RX, Rodrigues RR, McCulloch JA, Wang H, Hartman DJ, Badger JH, Fernandes MR, Bai Y, Sun J, Cole AM, Aggarwal P, Fang JR, Deitrick C, Bao R, Duvvuri U, Sridharan SS, Kim SW, A Choudry H, Holtzman MP, Pingpank JF, O’Toole JP, DeBlasio R, Jin Y, Ding Q, Gao W, Groetsch C, Pagliano O, Rose A, Urban C, Singh J, Divarkar P, Mauro D, Bobilev D, Wooldridge J, Krieg AM, Fury MG, Whiteaker JR, Zhao L, Paulovich AG, Najjar YG, Luke JJ, Kirkwood JM, Taube JM, Park HJ, Trinchieri G, Zarour HM. Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial. Cancer Cell. 2024 Nov 11;42(11):1898-1918.e12. PMID: 39486411.
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MacFawn IP, Magnon G, Gorecki G, Kunning S, Rashid R, Kaiza ME, Atiya H, Ruffin AT, Taylor S, Soong TR, Bao R, Coffman LG, Bruno TC. The activity of tertiary lymphoid structures in high grade serous ovarian cancer is governed by site, stroma, and cellular interactions. Cancer Cell. 2024 Nov 11;42(11):1864-1881.e5. PMID: 39393357.
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Pulmonary, Allergy, Critical Care, and Sleep Medicine
Iasella CJ, Hannan SJ, Lyons EJ, Lieber SC, Das A, Dimitrov D, Li W, Saul M, Popescu I, Koshy R, Burke R, Lape B, Brown MJ, Chen X, Sembrat JC, Devonshire K, Kitsios GD, Konstantinidis I, Snyder ME, Chen BB, Merlo CA, Hager DN, Kiss JE, Yazer MH, Wells AH, Morris A, McVerry BJ, McMahon DK, Triulzi DJ, McDyer JF. Impact of variable titer COVID-19 convalescent plasma and recipient SARS-CoV2-specific humoral immunity on survival in hospitalized patients. PLoS One. 2024 Oct 24;19(10):e0309449. PMID: 39446792.
Nath S, Qurashi H, Kitsios GD, Bain W, Aneis H, Suber T, Prendergast N, Hensley M, Schaefer C, Zhang Y, Bon J, McVerry BJ, Evankovich J, Shah FA. Clinical and biologic profiles of patients with acute respiratory distress syndrome by prevalence of chronic obstructive pulmonary disease or emphysema; a cohort study. Respir Res. 2024 Nov 8;25(1):400. PMID: 39516808.
Sui J, Xiao H, Mbaekwe U, Ting NC, Murday K, Hu Q, Gregory AD, Kapellos TS, Yildirim AÖ, Königshoff M, Zhang Y, Sciurba F, Das J, Kliment CR. Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD. JCI Insight. 2024 Nov 8;9(21):e180239. PMID: 39352744.
Renal-Electrolyte
Ruiz WG, Clayton DR, Parakala-Jain T, Dalghi MG, Franks J, Apodaca G. The rat bladder umbrella cell keratin network: Organization, dependence on the plectin cytolinker, and responses to bladder filling. Mol Biol Cell. 2024 Nov 1;35(11):ar139. PMID: 39356795.
Weltman MR, Lavenburg LU, Han Z, Alghwiri AA, Mosslemi M, Rollman BL, Fischer GS, Nolin TD, Yabes JG, Jhamb M. Population Health Management and Guideline-Concordant Care in CKD: A Secondary Analysis of Kidney Coordinated HeAlth Management Partnership. J Am Soc Nephrol. 2024 Nov 1. PMID: 39485493.
Manrique-Caballero CL, Barasch J, Zaidi SK, Bates CM, Ray EC, Kleyman TR, Al-Bataineh MM. Expression and Distribution of MUC1 in the Developing and Adult Kidney. Am J Physiol Renal Physiol. 2024 Nov 26. PMID: 39588770.
Rheumatology and Clinical Immunology
Aggarwal R, Lundberg IE, Song YW, Shaibani A, Werth VP, Maldonado MA. Efficacy and safety of subcutaneous abatacept + standard treatment for active idiopathic inflammatory myopathy: phase III randomised controlled trial. Arthritis Rheumatol. 2024 Nov 28. PMID: 39609094.
Sattui SE, Jiang B, Fu X, Cook C, Srivatsan S, Williams ZK, Katz G, Zhang Y, Wallace ZS. The effects of age and frailty on the risks of end-stage renal disease, death, and severe infection in older adults with antineutrophil cytoplasmic antibody-associated vasculitis: a retrospective cohort study. Lancet Rheumatol. 2024 Nov;6(11):e771-e779. PMID: 39305914.
Huang M, Tabib T, Khanna D, Assassi S, Domsic R, Lafyatis R. Single-cell transcriptomes and chromatin accessibility of endothelial cells unravel transcription factors associated with dysregulated angiogenesis in systemic sclerosis. Ann Rheum Dis. 2024 Sep 30;83(10):1335-1344. PMID: 38754983.
Vascular Medicine Institute
Liu Z, Ajam A, Huang J, Yeh YS, Razani B. Glutamine-glutamate imbalance in the pathogenesis of cardiovascular disease. Nat Cardiovasc Res. 2024 Nov 19. PMID: 39562783.
Chowdhury FA, Sharma M, Schafer D, Nouraie SM, Gladwin MT, Straub AC, Wood KC. CYB5R3 T117S tempers fetal hemoglobin induction by hydroxyurea in patients with sickle cell disease. Blood Adv. 2024 Dec 10;8(23):6098-6103. PMID: 39374579.
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Dustin CM, Shiva SS, Vazquez A, Saeed A, Pascoal T, Cifuentes-Pagano E, Pagano PJ. NOX2 in Alzheimer’s and Parkinson’s disease. Redox Biol. 2024 Dec;78:103433. PMID: 39616884.
Internal Medicine Residency
Pressimone C, Lane K, Ruppert K, Miller T, Gabriel C, Kyle J, Vanderberg R. The Development and Implementation of a Rheumatology Referral-Based, General Internal Medicine-Led Fibromyalgia Clinic and Preliminary Patient Outcomes. Musculoskeletal Care. 2024 Sep;22(3):e1935. PMID: 39261292.
Preisendörfer S, Ayub MT, Sheth A, Jabbour GY, Singh M, Patel CP, Gada H, Bhonsale A, Dhande M, Estes NA, Kancharla K, Kliner DE, Makani A, Naniwadekar A, Shalaby A, Singla V, Voigt A, Saba SF, Jain SK. Combined left atrial appendage occlusion and catheter ablation procedure for left atrial arrhythmias: A real-world, propensity-matched analysis. J Cardiovasc Electrophysiol. 2024 Oct 15. PMID: 39407419.
Christodoulou I, Rothenberger S, Ragni MV. Predictors of liver disease outcomes in individuals with hemophilia and HCV infection. Blood Adv. 2024 Nov 26;8(22):5767-5772. PMID: 39361728.